Assay Detail
Functional
CHEMBL4819445
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human Huh7 cells incubated for 48 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Huh-7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Recent advances of podophyllotoxin/epipodophyllotoxin hybrids in anticancer activity, mode of action, and structure-activity relationship: An update (2010-2020).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.22 | 7.22 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4206231 | — | — | 1 | 7.22 |
| CHEMBL4215547 | — | — | 1 | 7.22 |
| CHEMBL4847320 | — | — | 1 | 7.22 |
| CHEMBL4855168 | — | — | 1 | 7.22 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4206231 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL4215547 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL4847320 | — | IC50 | = | 60.0 | nM | 7.22 |
| CHEMBL4855168 | — | IC50 | = | 60.0 | nM | 7.22 |