Assay Detail
Functional
CHEMBL4819641
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antibacterial activity against Escherichia coli ATCC8739 assessed as inhibition of bacterial growth measured after 17 hrs by resazurin based flourimetric assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Escherichia coli |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and structure-activity studies of novel anhydrohexitol-based Leucyl-tRNA synthetase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.14 | 6.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200699 | DOXYCYCLINE | 4.0 | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200699 | DOXYCYCLINE | IC50 | = | 730.0 | nM | 6.14 |