Assay Detail
Binding
CHEMBL4822393
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human recombinant CA4 assessed as intrinsic dissociation constant by thermal shift assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Developments of small molecules as inhibitors for carbonic anhydrase isoforms.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 9.68 | 9.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4452277 | — | — | 1 | 9.89 |
| CHEMBL4439634 | — | — | 1 | 9.57 |
| CHEMBL4439909 | — | — | 1 | 9.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4452277 | — | Kd | = | 0.13 | nM | 9.89 |
| CHEMBL4439634 | — | Kd | = | 0.27 | nM | 9.57 |
| CHEMBL4439909 | — | Kd | = | 0.27 | nM | 9.57 |