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Assay Detail

CHEMBL4823913

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of CYP2C19 (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Cytochrome P450 2C19 (CHEMBL3622)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.
Shen S, Picci C, Ustinova K, Benoy V, Kutil Z, Zhang G, Tavares MT, Pavlíček J, Zimprich CA, Robers MB, Van Den Bosch L, Bařinka C, Langley B, Kozikowski AP.
J Med Chem (2021) 64 : 4810 -4840
PubMed 33830764 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.33 7.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4846435 1 7.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4846435 IC50 = 47.0 nM 7.33