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Assay Detail

CHEMBL4824770

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse splenocytes assessed as cell survival in presence of ConA measured after 44 hrs by CCK-8 assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type Splenocyte
Confidence 1 — Organism
Curated By Autocuration

Target

Splenocyte (CHEMBL612422)
Type CELL-LINE
Organism Mus musculus

Publication

Vomifoliol isolated from mangrove plant Ceriops tagal inhibits the NFAT signaling pathway with CN as the target enzyme in vitro.
Zhang X, Li G, Deng Q, Xu Z, Cen J, Xu J.
Bioorg Med Chem Lett (2021) 48 : 128235 -128235
PubMed 34216746 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.73 4.73
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL463088 BLUMENOL A 2 4.73

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL463088 BLUMENOL A IC50 = 18650.0 nM 4.73
CHEMBL463088 BLUMENOL A Activity - -