Assay Detail
Binding
CHEMBL4824896
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CYP2C19
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Conformational-Analysis-Guided Discovery of 2,3-Disubstituted Pyridine IDO1 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.25 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4786690 | — | — | 1 | 5.47 |
| CHEMBL4848094 | — | — | 1 | 5.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4786690 | — | IC50 | = | 3370.0 | nM | 5.47 |
| CHEMBL4848094 | — | IC50 | = | 9500.0 | nM | 5.02 |