Assay Detail
Functional
CHEMBL4825922
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Antiviral activity against Respiratory syncytial virus A2 infected in human Hep2 cells by Plaque reduction assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human respiratory syncytial virus |
| Cell Type | HEp-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 7.95 | 9.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4855358 | — | — | 1 | 9.30 |
| CHEMBL4847062 | — | — | 1 | 7.86 |
| CHEMBL4866951 | — | — | 1 | 7.68 |
| CHEMBL4871056 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4855358 | — | EC50 | = | 0.5 | nM | 9.30 |
| CHEMBL4847062 | — | EC50 | = | 13.7 | nM | 7.86 |
| CHEMBL4866951 | — | EC50 | = | 21.1 | nM | 7.68 |
| CHEMBL4871056 | — | EC50 | = | 106.7 | nM | 6.97 |