Assay Detail
Binding
CHEMBL4825974
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Respiratory syncytial virus fusion protein
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Human respiratory syncytial virus |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Fusion glycoprotein F0 (CHEMBL3856166) ↗| Type | SINGLE PROTEIN |
| Organism | Human respiratory syncytial virus A (strain A2) |
Publication
Discovery of Sisunatovir (RV521), an Inhibitor of Respiratory Syncytial Virus Fusion.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.06 | 9.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4876200 | — | — | 1 | 9.16 |
| CHEMBL4871101 | — | — | 1 | 9.05 |
| CHEMBL4858040 | — | — | 1 | 9.05 |
| CHEMBL4858949 | — | — | 1 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4876200 | — | IC50 | = | 0.69 | nM | 9.16 |
| CHEMBL4871101 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL4858040 | — | IC50 | = | 0.9 | nM | 9.05 |
| CHEMBL4858949 | — | IC50 | = | 1.1 | nM | 8.96 |