Assay Detail
Binding
CHEMBL4827748
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Binding affinity to Mycobacterium tuberculosis CYP124A1 by UV-visible spectrophotometric analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycobacterium tuberculosis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Synthesis and interaction of terminal unsaturated chemical probes with Mycobacterium tuberculosis CYP124A1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 7 | 5.39 | 6.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4853893 | — | — | 1 | 6.66 |
| CHEMBL25308 | FARNESOL | — | 1 | 5.98 |
| CHEMBL4864160 | — | — | 1 | 5.82 |
| CHEMBL4864063 | — | — | 1 | 5.54 |
| CHEMBL4866243 | — | — | 1 | 4.84 |
| CHEMBL25719 | GERANIOL | — | 1 | 4.60 |
| CHEMBL4846891 | — | — | 1 | 4.31 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4853893 | — | Kd | = | 220.0 | nM | 6.66 |
| CHEMBL25308 | FARNESOL | Kd | = | 1040.0 | nM | 5.98 |
| CHEMBL4864160 | — | Kd | = | 1500.0 | nM | 5.82 |
| CHEMBL4864063 | — | Kd | = | 2900.0 | nM | 5.54 |
| CHEMBL4866243 | — | Kd | = | 14600.0 | nM | 4.84 |
| CHEMBL25719 | GERANIOL | Kd | = | 25000.0 | nM | 4.60 |
| CHEMBL4846891 | — | Kd | = | 49400.0 | nM | 4.31 |