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Compound Detail

CHEMBL4864063

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C=CCOC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CO

Basic Information

ChEMBL ID CHEMBL4864063
Phase Preclinical
Structure Type MOL
InChI Key MFLOHLWWWWKJGI-SZPHWZFISA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

278.4
MW (Da)
4.58
ALogP
2
HBA
1
HBD
29.5
PSA (Ų)
0.44
QED
0
Ro5 Violations
11
Rot. Bonds

Drug Information

Molecule Type Unknown
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C18H30O2
MW 278.44
Aromatic Rings 0
Heavy Atoms 20
NP-Likeness 1.49

Activity Summary

Kd 1 meas. best 5.54

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
Kd 5.54 5.54 2900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked Kd = 2900.0 nM 5.54 Binding affinity to Mycobacterium tuberculosis CYP124A1 by UV-visible spectropho... 34289431

Literature References

PubMed DOI Target Context # Activities
34289431 10.1016/j.bmc.2021.116304 Unchecked 3

Data from ChEMBL 36 via Core Engine