Assay Detail
Binding
CHEMBL4828355
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Binding affinity to 5HT1B receptor (unknown origin)
22
Total Activities
22
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of G Protein-Biased Antagonists against 5-HT<sub>7</sub>R.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 22 | 5.69 | 5.99 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4877051 | — | — | 1 | 5.99 |
| CHEMBL4852622 | — | — | 1 | 5.86 |
| CHEMBL4856702 | — | — | 1 | 5.74 |
| CHEMBL4863868 | — | — | 1 | 5.45 |
| CHEMBL4877603 | — | — | 1 | 5.41 |
| CHEMBL4854605 | — | — | 1 | - |
| CHEMBL4866412 | — | — | 1 | - |
| CHEMBL4869695 | — | — | 1 | - |
| CHEMBL4867560 | — | — | 1 | - |
| CHEMBL4860503 | — | — | 1 | - |
| CHEMBL4863036 | — | — | 1 | - |
| CHEMBL4868035 | — | — | 1 | - |
| CHEMBL4876036 | — | — | 1 | - |
| CHEMBL4870675 | — | — | 1 | - |
| CHEMBL4862745 | — | — | 1 | - |
| CHEMBL4859827 | — | — | 1 | - |
| CHEMBL4848305 | — | — | 1 | - |
| CHEMBL4858338 | — | — | 1 | - |
| CHEMBL4874854 | — | — | 1 | - |
| CHEMBL4871980 | — | — | 1 | - |
| CHEMBL4876193 | — | — | 1 | - |
| CHEMBL282199 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4877051 | — | Ki | = | 1018.0 | nM | 5.99 |
| CHEMBL4852622 | — | Ki | = | 1378.0 | nM | 5.86 |
| CHEMBL4856702 | — | Ki | = | 1819.0 | nM | 5.74 |
| CHEMBL4863868 | — | Ki | = | 3585.0 | nM | 5.45 |
| CHEMBL4877603 | — | Ki | = | 3915.0 | nM | 5.41 |
| CHEMBL4854605 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4866412 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4869695 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4867560 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4860503 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4863036 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4868035 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4876036 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4870675 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4862745 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4859827 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4848305 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4858338 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4874854 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4871980 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL4876193 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL282199 | — | Ki | > | 10000.0 | nM | - |