Compound Detail
CHEMBL4877603
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Basic Information
| ChEMBL ID | CHEMBL4877603 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QYUZYZBBJGTSFR-UHFFFAOYSA-N |
8
Targets
11
Activities
2
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
276.8
MW (Da)
2.53
ALogP
3
HBA
2
HBD
44.0
PSA (Ų)
0.89
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 9 meas. best 8.19
IC50 2 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | Ki | 8.19 | 8.185 | 6.5 | 2 |
| 5-hydroxytryptamine receptor 3A CHEMBL1899 | Ki | 6.52 | 6.52 | 300.0 | 1 |
| 5-hydroxytryptamine receptor 1A CHEMBL214 | Ki | 6.39 | 6.39 | 411.0 | 1 |
| 5-hydroxytryptamine receptor 2B CHEMBL1833 | Ki | 6.38 | 6.38 | 416.0 | 1 |
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 6.28 | 6.28 | 529.0 | 1 |
| 5-hydroxytryptamine receptor 7 CHEMBL3155 | IC50 | 6.16 | 6.16 | 686.0 | 2 |
| 5-hydroxytryptamine receptor 2A CHEMBL224 | Ki | 6.05 | 6.05 | 894.0 | 1 |
| 5-hydroxytryptamine receptor 1D CHEMBL1983 | Ki | 5.69 | 5.69 | 2029.0 | 1 |
| 5-hydroxytryptamine receptor 1B CHEMBL1898 | Ki | 5.41 | 5.41 | 3915.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
Literature References
Data from ChEMBL 36 via Core Engine