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Assay Detail

CHEMBL4832251

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Binding
Binding affinity to galectin-8 N-terminal domain (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Galectin-8 (CHEMBL5475)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Benzimidazole-galactosides bind selectively to the Galectin-8 N-Terminal domain: Structure-based design and optimisation.
Hassan M, van Klaveren S, Håkansson M, Diehl C, Kovačič R, Baussière F, Sundin AP, Dernovšek J, Walse B, Zetterberg F, Leffler H, Anderluh M, Tomašič T, Jakopin Ž, Nilsson UJ.
Eur J Med Chem (2021) 223 : 113664 -113664
PubMed 34225180 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 3 5.82 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4854378 1 5.82
CHEMBL4847180 1 -
CHEMBL4853061 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4854378 Kd = 1500.0 nM 5.82
CHEMBL4847180 Kd = 700000.0 nM -
CHEMBL4853061 Kd = 110000.0 nM -