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Assay Detail

CHEMBL4835146

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antibacterial activity against Staphylococcus aureus ATCC6538
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Staphylococcus aureus
Confidence 1 — Organism
Curated By Autocuration

Target

Staphylococcus aureus (CHEMBL352)
Type ORGANISM
Organism Staphylococcus aureus

Publication

Antiplasmodial Oleanane Triterpenoids from <i>Terminalia albida</i> Root Bark.
Baldé MA, Tuenter E, Traoré MS, Peeters L, Matheeussen A, Cos P, Caljon G, Vermeyen T, Herrebout W, Balde AM, Foubert K, Pieters L.
J Nat Prod (2021) 84 : 666 -675
PubMed 33667089 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 6.55 6.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1200699 DOXYCYCLINE 4.0 1 6.55
CHEMBL4851778 1 -
CHEMBL4853624 1 -
CHEMBL4876283 1 -
CHEMBL4852152 1 -
CHEMBL4873325 1 -
CHEMBL4864142 1 -
CHEMBL4869593 1 -
CHEMBL4854639 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1200699 DOXYCYCLINE IC50 = 280.0 nM 6.55
CHEMBL4851778 IC50 > 64000.0 nM -
CHEMBL4853624 IC50 > 64000.0 nM -
CHEMBL4876283 IC50 > 64000.0 nM -
CHEMBL4852152 IC50 > 64000.0 nM -
CHEMBL4873325 IC50 > 64000.0 nM -
CHEMBL4864142 IC50 > 64000.0 nM -
CHEMBL4869593 IC50 > 64000.0 nM -
CHEMBL4854639 IC50 > 64000.0 nM -