Assay Detail
Functional
CHEMBL4838790
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Cytotoxicity against human U-87MG cells assessed as cell growth inhibition measured after 48 hrs by MTS colorimetric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-87MG ATCC |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of pyrrole derivatives for the treatment of glioblastoma and chronic myeloid leukemia.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.56 | 7.71 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4864675 | — | — | 1 | 7.71 |
| CHEMBL4854987 | — | — | 1 | 7.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4864675 | — | IC50 | = | 19.4 | nM | 7.71 |
| CHEMBL4854987 | — | IC50 | = | 39.1 | nM | 7.41 |