Assay Detail
Binding
CHEMBL4839422
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of wild-type human partial length SLK (S14 to A307 residues) expressed in bacterial expression system by Kinomescan method relative to control
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
STE20-like serine/threonine-protein kinase (CHEMBL4202) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 6.11 | 6.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL156563 | — | — | 1 | 6.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL156563 | — | Kd | = | 770.0 | nM | 6.11 |