STE20-like serine/threonine-protein kinase · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q9H2G2. Use UniProt Q9H2G2 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9H2G2 as the stable identity anchor, then attach disease evidence before program review.
STE20-like serine/threonine-protein kinase
Review this target as STE20-like serine/threonine-protein kinase, mapped to UniProt Q9H2G2. Sequence length is 1235 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats STE20-like serine/threonine-protein kinase as ChEMBL target CHEMBL4202, mapped to UniProt Q9H2G2. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | STE20-like serine/threonine-protein kinase |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9H2G2 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | STE20-like serine/threonine-protein kinase |
| UniProt Accession | Q9H2G2 |
| Component Type | Protein |
| Sequence Length | 1235 aa |
STE20-like serine/threonine-protein kinase
Review this target as STE20-like serine/threonine-protein kinase, mapped to UniProt Q9H2G2. Sequence length is 1235 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 10.7 | Kd | 0.02 | Preclinical |
| CHEMBL1230609 | 8.52 | Kd | 3.0 | Clinical |
| CHEMBL4875188 | 8.43 | Ki | 3.7 | Preclinical |
| CHEMBL4878325 | 8.41 | Ki | 3.9 | Preclinical |
| CHEMBL288441 | 8.33 | Kd | 4.7 | Approved |
| CHEMBL1974328 | 8.3 | Ki | 5.012 | Preclinical |
| CHEMBL509032 | 8.3 | Ki | 5.012 | Preclinical |
| CHEMBL4465866 | 8.3 | Kd | 5.0 | Preclinical |
| CHEMBL4877889 | 8.22 | Ki | 6.0 | Preclinical |
| CHEMBL4576489 | 8.22 | Kd | 6.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 177 | 147 | 6.8 |
| assay format | 34 | 5 | 7.0 |
| subcellular format | 34 | 50 | 5.7 |
| cell-based format | 29 | 6 | 6.3 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 300 | 6.2 |