Compound Detail
CHEMBL4465866
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CO[C@@H]1[C@H](NCCOCCOCCOCCNC(=O)CCC2=[N+]3C(=Cc4c(C)cc(C)n4[B-]3(F)F)C=C2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4
Basic Information
| ChEMBL ID | CHEMBL4465866 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NXSJMRCTGYTSTK-SQHKIPTKSA-N |
201
Targets
201
Activities
1
Assay Types
0
PK Parameters
20
Publications
0
Known Names
Molecular Properties
901.8
MW (Da)
Drug Information
| Molecule Type | Unknown |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 201 meas. best 9.0
Target Activity Profile
Activity Data Samples
Top measurements by pChEMBL value
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 31526603 | 10.1016/j.bmcl.2019.126641 | Tyrosine-protein kinase ZAP-70 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Homeodomain-interacting protein kinase 2 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Tyrosine-protein kinase TXK | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Proto-oncogene tyrosine-protein kinase ROS | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Ephrin type-B receptor 4 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Dual specificity mitogen-activated protein kinase kinase 7 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Cyclin-dependent kinase 5/CDK5 activator 1 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Serine/threonine-protein kinase pim-2 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Ephrin type-B receptor 2 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | cAMP-dependent protein kinase catalytic subunit PRKX | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Ephrin type-A receptor 3 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Serine/threonine-protein kinase Chk1 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Myosin light chain kinase | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | MAP/microtubule affinity-regulating kinase 4 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Serine/threonine-protein kinase MRCK gamma | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Ephrin type-A receptor 4 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Serine/threonine-protein kinase Chk2 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Serine/threonine-protein kinase pim-3 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Tyrosine-protein kinase JAK2 | 1 |
| 31526603 | 10.1016/j.bmcl.2019.126641 | Tyrosine-protein kinase ABL1 | 1 |
Data from ChEMBL 36 via Core Engine