Serine/threonine-protein kinase 33 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q9BYT3. Use UniProt Q9BYT3 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q9BYT3 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase 33
Review this target as Serine/threonine-protein kinase 33, mapped to UniProt Q9BYT3. Sequence length is 514 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase 33 as ChEMBL target CHEMBL6005, mapped to UniProt Q9BYT3. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase 33 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q9BYT3 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase 33 |
| UniProt Accession | Q9BYT3 |
| Component Type | Protein |
| Sequence Length | 514 aa |
Serine/threonine-protein kinase 33
Review this target as Serine/threonine-protein kinase 33, mapped to UniProt Q9BYT3. Sequence length is 514 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 8.74 | Kd | 1.8 | Preclinical |
| CHEMBL509032 | 8.49 | Kd | 3.2 | Preclinical |
| CHEMBL4576489 | 8.22 | Kd | 6.0 | Preclinical |
| CHEMBL2203524 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL4465866 | 8.1 | Kd | 8.0 | Preclinical |
| CHEMBL2203525 | 7.96 | IC50 | 11.0 | Preclinical |
| CHEMBL2204239 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL535 | 7.77 | Kd | 17.0 | Approved |
| CHEMBL603469 | 7.58 | Kd | 26.0 | Clinical |
| CHEMBL388978 | 7.44 | IC50 | 36.3 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 173 | 58 | 6.5 |
| assay format | 23 | 0 | — |
| cell-based format | 10 | 3 | 7.0 |
| subcellular format | 4 | 0 | — |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 5 | 5.7 |