Serine/threonine-protein kinase N2 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q16513. Use UniProt Q16513 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16513 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase N2
Review this target as Serine/threonine-protein kinase N2, mapped to UniProt Q16513. Sequence length is 984 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase N2 as ChEMBL target CHEMBL3032, mapped to UniProt Q16513. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase N2 is the right protein anchor across sources, using UniProt Q16513 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase N2 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16513 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase N2 |
| UniProt Accession | Q16513 |
| Component Type | Protein |
| Sequence Length | 984 aa |
Serine/threonine-protein kinase N2
Review this target as Serine/threonine-protein kinase N2, mapped to UniProt Q16513. Sequence length is 984 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL1980995 | 9.1 | Ki | 0.7943 | Preclinical |
| CHEMBL603469 | 8.74 | Kd | 1.8 | Clinical |
| CHEMBL388978 | 8.71 | IC50 | 1.97 | Preclinical |
| CHEMBL1969588 | 8.6 | Ki | 2.512 | Preclinical |
| CHEMBL1968930 | 8.6 | Ki | 2.512 | Preclinical |
| CHEMBL1998432 | 8.6 | Ki | 2.512 | Preclinical |
| CHEMBL388978 | 8.6 | Kd | 2.5 | Preclinical |
| CHEMBL4576489 | 8.4 | Kd | 4.0 | Preclinical |
| CHEMBL1970903 | 8.3 | Ki | 5.012 | Preclinical |
| CHEMBL225519 | 8.3 | Ki | 5.012 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 269 | 83 | 6.3 |
| cell-based format | 24 | 8 | 6.2 |
| assay format | 17 | 0 | — |
| subcellular format | 15 | 15 | 6.5 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 283 | 6.3 |