Use UniProt Q13555 as the stable identity anchor, then attach disease evidence before program review.
CHEMBL3829 Target Snapshot
Calcium/calmodulin-dependent protein kinase type II subunit gamma · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt Q13555. Use UniProt Q13555 as the stable identity anchor, then attach disease evidence before program review.
Calcium/calmodulin-dependent protein kinase type II subunit gamma
Review this target as Calcium/calmodulin-dependent protein kinase type II subunit gamma, mapped to UniProt Q13555. Sequence length is 558 aa.
Protein source · UniProt accession via ChEMBL component mappingCross-source identity
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This review treats Calcium/calmodulin-dependent protein kinase type II subunit gamma as ChEMBL target CHEMBL3829, mapped to UniProt Q13555. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13555 |
Next Actions
UniProt Target Context
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Calcium/calmodulin-dependent protein kinase type II subunit gamma |
| UniProt Accession | Q13555 |
| Component Type | Protein |
| Sequence Length | 558 aa |
Calcium/calmodulin-dependent protein kinase type II subunit gamma
How to read this target
Review this target as Calcium/calmodulin-dependent protein kinase type II subunit gamma, mapped to UniProt Q13555. Sequence length is 558 aa.
Clinical Phase Distribution
Activity Type Distribution
Top Inhibitors (by pChEMBL)
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.44 | IC50 | 0.366 | Preclinical |
| CHEMBL388978 | 9.3 | Kd | 0.5 | Preclinical |
| CHEMBL3683258 | 9.15 | IC50 | 0.7 | Preclinical |
| CHEMBL4556306 | 9.1 | IC50 | 0.79 | Preclinical |
| CHEMBL1966628 | 8.4 | Ki | 3.981 | Preclinical |
| CHEMBL1974870 | 8.4 | Ki | 3.981 | Preclinical |
| CHEMBL4465866 | 8.1 | Kd | 8.0 | Preclinical |
| CHEMBL4576489 | 8.05 | Kd | 9.0 | Preclinical |
| CHEMBL1998159 | 8.0 | Ki | 10.0 | Preclinical |
| CHEMBL5653589 | 7.95 | Kd | 11.22 | Preclinical |
pChEMBL Value Distribution
Approved Drugs
Assay Landscape
Binding — 257 assays, 51 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 157 | 32 | 6.7 |
| cell-based format | 36 | 2 | 8.1 |
| subcellular format | 33 | 17 | 6.3 |
| assay format | 31 | 0 | — |
Functional — 1 assays, 213 compounds
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 1 | 213 | 5.9 |