Serine/threonine-protein kinase N1 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q16512. Use UniProt Q16512 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q16512 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase N1
Review this target as Serine/threonine-protein kinase N1, mapped to UniProt Q16512. Sequence length is 942 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase N1 as ChEMBL target CHEMBL3384, mapped to UniProt Q16512. Disease framing currently uses the Open Targets-ready proxy contract.
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Start here when your first question is whether Serine/threonine-protein kinase N1 is the right protein anchor across sources, using UniProt Q16512 as the stable mapping.
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| Preferred Name | Serine/threonine-protein kinase N1 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q16512 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase N1 |
| UniProt Accession | Q16512 |
| Component Type | Protein |
| Sequence Length | 942 aa |
Serine/threonine-protein kinase N1
Review this target as Serine/threonine-protein kinase N1, mapped to UniProt Q16512. Sequence length is 942 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.7 | IC50 | 0.199 | Preclinical |
| CHEMBL3597011 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5687042 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL388978 | 8.89 | Kd | 1.3 | Preclinical |
| CHEMBL5687026 | 8.8 | IC50 | 1.6 | Preclinical |
| CHEMBL5687057 | 8.4 | IC50 | 4.0 | Preclinical |
| CHEMBL5687053 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL603469 | 8.28 | Kd | 5.3 | Clinical |
| CHEMBL4576489 | 8.22 | Kd | 6.0 | Preclinical |
| CHEMBL1214929 | 8.15 | IC50 | 7.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 210 | 87 | 6.3 |
| assay format | 25 | 5 | 5.3 |
| subcellular format | 17 | 37 | 6.2 |
| cell-based format | 11 | 2 | 8.1 |