Compound Detail
CHEMBL5687026
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Basic Information
| ChEMBL ID | CHEMBL5687026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JDQPBXZXEOUYLD-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
410.9
MW (Da)
4.62
ALogP
6
HBA
3
HBD
98.4
PSA (Ų)
0.41
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase N1 CHEMBL3384 | IC50 | 8.8 | 8.8 | 1.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase N1 | IC50 | = | 1.6 | nM | 8.8 | Inhibition of PAK1 (unknown origin) | 25415869 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25415869 | 10.1021/jm501613q | Serine/threonine-protein kinase N1 | 1 |
Data from ChEMBL 36 via Core Engine