Serine/threonine-protein kinase 4 · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt Q13043. Use UniProt Q13043 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt Q13043 as the stable identity anchor, then attach disease evidence before program review.
Serine/threonine-protein kinase 4
Review this target as Serine/threonine-protein kinase 4, mapped to UniProt Q13043. Sequence length is 487 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Serine/threonine-protein kinase 4 as ChEMBL target CHEMBL4598, mapped to UniProt Q13043. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Serine/threonine-protein kinase 4 |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | Q13043 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Serine/threonine-protein kinase 4 |
| UniProt Accession | Q13043 |
| Component Type | Protein |
| Sequence Length | 487 aa |
Serine/threonine-protein kinase 4
Review this target as Serine/threonine-protein kinase 4, mapped to UniProt Q13043. Sequence length is 487 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL388978 | 9.72 | EC50 | 0.19 | Preclinical |
| CHEMBL388978 | 9.72 | Kd | 0.19 | Preclinical |
| CHEMBL388978 | 8.99 | IC50 | 1.02 | Preclinical |
| CHEMBL603469 | 8.52 | Kd | 3.0 | Clinical |
| CHEMBL4576489 | 8.4 | Kd | 4.0 | Preclinical |
| CHEMBL4116008 | 8.4 | IC50 | 4.0 | Clinical |
| CHEMBL4465866 | 8.15 | Kd | 7.0 | Preclinical |
| CHEMBL502835 | 8.05 | Kd | 9.0 | Approved |
| CHEMBL4554938 | 8.01 | IC50 | 9.8 | Preclinical |
| CHEMBL608533 | 7.77 | Kd | 17.0 | Approved |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 228 | 146 | 6.3 |
| cell-based format | 39 | 86 | 6.3 |
| assay format | 36 | 30 | 6.9 |
| subcellular format | 20 | 28 | 6.1 |