Assay Detail
Binding
CHEMBL4839432
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of GSK3alpha (unknown origin) assessed as transfer of radiolabelled phosphate group from ATP by reaction biology method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a Potent Dual SLK/STK10 Inhibitor Based on a Maleimide Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.95 | 8.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | — | 1 | 8.29 |
| CHEMBL156277 | — | — | 1 | 7.85 |
| CHEMBL4875188 | — | — | 1 | 7.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL388978 | STAUROSPORINE | IC50 | = | 5.1 | nM | 8.29 |
| CHEMBL156277 | — | IC50 | = | 14.0 | nM | 7.85 |
| CHEMBL4875188 | — | IC50 | = | 19.0 | nM | 7.72 |