Assay Detail
Functional
CHEMBL4840835
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Partial agonist activity at human CB2 receptor transfected in CHO cells incubated for 90 mins by scintillation counting based [35S]GTP-gamma-S-binding assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Δ<sup>9</sup>-<i>cis</i>-Tetrahydrocannabinol: Natural Occurrence, Chirality, and Pharmacology.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.42 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL465 | DRONABINOL | 4.0 | 1 | 7.92 |
| CHEMBL4845760 | — | — | 1 | 6.92 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL465 | DRONABINOL | EC50 | = | 12.0 | nM | 7.92 |
| CHEMBL4845760 | — | EC50 | = | 119.0 | nM | 6.92 |