Assay Detail
Functional
CHEMBL4842235
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Cytotoxicity against human HCT-116 cells assessed as reduction in cell viability after 72 hrs by MTT assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cytochalasin Derivatives from the Endozoic <i>Curvularia verruculosa</i> CS-129, a Fungus Isolated from the Deep-Sea Squat Lobster <i>Shinkaia crosnieri</i> Living in the Cold Seep Environment.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.02 | 5.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2253152 | DEOXAPHOMIN | — | 1 | 5.12 |
| CHEMBL4848578 | — | — | 1 | 5.02 |
| CHEMBL411729 | CYTOCHALASIN B | — | 1 | 4.92 |
| CHEMBL4858162 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2253152 | DEOXAPHOMIN | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL4848578 | — | IC50 | = | 9500.0 | nM | 5.02 |
| CHEMBL411729 | CYTOCHALASIN B | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL4858162 | — | IC50 | - | — | - |