Assay Detail
Functional
CHEMBL4842459
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Respiratory syncytial virus assessed as reduction in virus-induced cytopathic effect by MTS assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
Phenoxazine nucleoside derivatives with a multiple activity against RNA and DNA viruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 16 | 5.33 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | 4.0 | 1 | 5.70 |
| CHEMBL4873788 | — | — | 1 | 4.96 |
| CHEMBL4853972 | — | — | 1 | - |
| CHEMBL4852062 | — | — | 1 | - |
| CHEMBL4859942 | — | — | 1 | - |
| CHEMBL4876346 | — | — | 1 | - |
| CHEMBL4876888 | — | — | 1 | - |
| CHEMBL4867320 | — | — | 1 | - |
| CHEMBL4873641 | — | — | 1 | - |
| CHEMBL4846008 | — | — | 1 | - |
| CHEMBL4878050 | — | — | 1 | - |
| CHEMBL4857025 | — | — | 1 | - |
| CHEMBL4875977 | — | — | 1 | - |
| CHEMBL4865141 | — | — | 1 | - |
| CHEMBL4872020 | — | — | 1 | - |
| CHEMBL4870983 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1643 | RIBAVIRIN | EC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4873788 | — | EC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL4853972 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4852062 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4859942 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4876346 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4876888 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4867320 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4873641 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4846008 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4878050 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4857025 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4875977 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4865141 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4872020 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL4870983 | — | EC50 | > | 100000.0 | nM | - |