Assay Detail
Functional
CHEMBL4843382
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Antiviral activity against Zika virus
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Zika virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.13 | 5.19 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446364 | — | — | 1 | 5.19 |
| CHEMBL4874402 | — | — | 1 | 5.06 |
| CHEMBL4871225 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446364 | — | EC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL4874402 | — | EC50 | = | 8700.0 | nM | 5.06 |
| CHEMBL4871225 | — | EC50 | - | — | - |