Assay Detail

CHEMBL4880941

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Proliferation assay: BT-474 (breast cancer)

ChEMBL ↗

Free Research Context This assay will appear in recent viewed items on this browser. Open the demo workspace to preview project-only review queues.

Research home Demo workspace

Target

BT-474 (CHEMBL614529) ↗

Open DB target context

Use one target anchor to keep assay intent, target linkage, and tested compound review aligned.

Loading context

BT-474 (CHEMBL614529) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target BT-474

CHEMBL614529

Anchored from Assay target.

Protein identity BT-474

Disease frame Disease evidence pending

Open the live target snapshot or evidence card before reviewing assay metadata so target fit and disease framing stay reusable.

Review focus Open DB context pending

Open the live target snapshot before relying on this target frame across surface handoff.

Open target snapshot Open evidence card Search with this context

Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	BT-474
Confidence	1 — Organism
Curated By	Autocuration

Target

BT-474 (CHEMBL614529) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Data for DCP probe BAY-885

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	4.56	4.56

Assay Parameters

Parameter	Type	Value	Units	Text
Additional information	Additional information	-	—	Cell viability was determined with a CellTiter-Glo® luminescent assay

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4455582	BAY-693	—	1	4.56
CHEMBL4445670	BAY-885	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4455582	BAY-693	IC50	=	27600.0	nM	4.56
CHEMBL4445670	BAY-885	IC50	>	30000.0	nM	-