Assay Detail
Binding
CHEMBL4881419
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cellular mechanistic assay: inhibition of TEK autophosphorylation in human umbilical vein endothelial cells (HUVEC), pTEK-ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | HUVEC |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe BAY-826
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 8.89 | 8.89 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 27787897 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3907057 | BAY-826 | — | 1 | 8.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3907057 | BAY-826 | EC50 | = | 1.3 | nM | 8.89 |