Assay Detail
Binding
CHEMBL4882630
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Prostanoid receptor binding assay (PTGDR2)
2
Total Activities
2
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe CRTH2 antagonist, MK-7246
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.28 | 8.60 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 10634944 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL561132 | MK-7246 | 1.0 | 1 | 8.60 |
| CHEMBL1643772 | CRTH2-negative-control | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL561132 | MK-7246 | Ki | = | 2.5 | nM | 8.60 |
| CHEMBL1643772 | CRTH2-negative-control | Ki | = | 1083.0 | nM | 5.96 |