Assay Detail

CHEMBL4882992

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Binding

NanoBRET (SGC Frankfurt) (MAPK14)

ChEMBL ↗

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Target

Mitogen-activated protein kinase 14 (CHEMBL260) ↗

Open DB target context

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Mitogen-activated protein kinase 14 (CHEMBL260) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Mitogen-activated protein kinase 14

CHEMBL260

Anchored from Assay target.

Protein identity Mitogen-activated protein kinase 14

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Mitogen-activated protein kinase 14 (CHEMBL260) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe PPTN

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	2	6.50	6.50

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL4802050	8RK64	—	1	6.50
CHEMBL1800685	PPTN	—	1	-

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL4802050	8RK64	IC50	=	320.0	nM	6.50
CHEMBL1800685	PPTN	IC50	>	20000.0	nM	-