Assay Detail

CHEMBL4883091

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Binding

Glutamate dehydrogenase-coupled FAAH assay (preincubation time 60 min)

ChEMBL ↗

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Target

Fatty-acid amide hydrolase 1 (CHEMBL2243) ↗

Open DB target context

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Fatty-acid amide hydrolase 1 (CHEMBL2243) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Fatty-acid amide hydrolase 1

CHEMBL2243

Anchored from Assay target.

Protein identity Fatty-acid amide hydrolase 1

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Homo sapiens
Confidence	9 — Direct single protein target
Curated By	Autocuration

Target

Fatty-acid amide hydrolase 1 (CHEMBL2243) ↗

Type	SINGLE PROTEIN
Organism	Homo sapiens

Publication

Data for DCP probe PF-04457845

SGC Frankfurt
(2021)
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.13	8.13

Assay Parameters

Parameter	Type	Value	Units	Text
Assay publication	Assay publication	-	—	PMID: 21505060

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL1651534	REDAFAMDASTAT	2.0	1	8.13

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL1651534	REDAFAMDASTAT	IC50	=	7.4	nM	8.13