Assay Detail
Binding
CHEMBL4883185
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Thin Layer Chromatography (TLC) assay (human ACAT1)
1
Total Activities
1
Compounds Tested
1
Activity Types
3
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Acetyl-CoA acetyltransferase, mitochondrial (CHEMBL2616) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe TP-020
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 4.72 | 4.72 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Cell-free enzyme assay |
| Assay publication | Assay publication | - | — | PMID: 26100443 |
| Target protein length | Target protein length | - | — | full-length |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4455357 | TP-020 | — | 1 | 4.72 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4455357 | TP-020 | IC50 | = | 19000.0 | nM | 4.72 |