Acetyl-CoA acetyltransferase, mitochondrial · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-13Protein identity stays anchored to UniProt P24752. Use UniProt P24752 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P24752 as the stable identity anchor, then attach disease evidence before program review.
Acetyl-CoA acetyltransferase, mitochondrial
Review this target as Acetyl-CoA acetyltransferase, mitochondrial, mapped to UniProt P24752. Sequence length is 427 aa.
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This review treats Acetyl-CoA acetyltransferase, mitochondrial as ChEMBL target CHEMBL2616, mapped to UniProt P24752. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Acetyl-CoA acetyltransferase, mitochondrial |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P24752 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Acetyl-CoA acetyltransferase, mitochondrial |
| UniProt Accession | P24752 |
| Component Type | Protein |
| Sequence Length | 427 aa |
Acetyl-CoA acetyltransferase, mitochondrial
Review this target as Acetyl-CoA acetyltransferase, mitochondrial, mapped to UniProt P24752. Sequence length is 427 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL2105855 | 7.52 | IC50 | 30.0 | Clinical |
| CHEMBL573970 | 7.51 | IC50 | 31.0 | Preclinical |
| CHEMBL33780 | 7.36 | IC50 | 44.0 | Preclinical |
| CHEMBL5203276 | 7.35 | IC50 | 45.0 | Preclinical |
| CHEMBL1908306 | 7.23 | IC50 | 59.0 | Clinical |
| CHEMBL47095 | 7.01 | IC50 | 97.0 | Preclinical |
| CHEMBL22373 | 6.95 | IC50 | 112.0 | Preclinical |
| CHEMBL5542126 | 6.95 | IC50 | 113.0 | Preclinical |
| CHEMBL46423 | 6.74 | IC50 | 183.0 | Clinical |
| CHEMBL274185 | 6.62 | IC50 | 239.0 | Clinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 7 | 12 | 6.7 |
| cell-based format | 4 | 2 | 6.5 |