Assay Detail
Functional
CHEMBL4883623
Review assay metadata, readout intent, target linkage, and publication context from the same page.
CellTiter-Glo Luminescent Cell Viability Assay with RS4-11 cells (BCL-2 dependent cell line)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | RS4-11 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Data for DCP probe A-1211212
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 8.22 | 8.22 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Apoptosis test: 10% HS/ 48 hr |
| Target protein type | Target protein type | - | — | BCL-2 dependent cell line: RS4-11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4228713 | A-1211212 | — | 1 | 8.22 |
| CHEMBL4551344 | A-1210227 | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4228713 | A-1211212 | EC50 | = | 6.0 | nM | 8.22 |
| CHEMBL4551344 | A-1210227 | EC50 | > | 5000.0 | nM | - |