Assay Detail
Binding
CHEMBL4884602
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TR-FRET (mouse RIPK1)
3
Total Activities
3
Compounds Tested
1
Activity Types
1
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Receptor-interacting serine/threonine-protein kinase 1 (CHEMBL3784911) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Data for DCP probe TP-030-1
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.19 | 7.00 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 29485864 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4549667 | TP-030-2 | — | 1 | 7.00 |
| CHEMBL4088216 | TP-030-1 | — | 1 | 5.38 |
| CHEMBL4097778 | TP-030n | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4549667 | TP-030-2 | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4088216 | TP-030-1 | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL4097778 | TP-030n | IC50 | > | 10000.0 | nM | - |