Assay Detail
Binding
CHEMBL4885666
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BET mutant TR-FRET assay (BRD2 BD2)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe GSK789
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.75 | 4.80 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Assay publication | Assay publication | - | — | PMID: 32691589 |
| Target protein length | Target protein length | - | — | BD2 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4635540 | GSK791 | — | 1 | 4.80 |
| CHEMBL4648362 | GSK789 | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4635540 | GSK791 | IC50 | = | 15848.93 | nM | 4.80 |
| CHEMBL4648362 | GSK789 | IC50 | = | 19952.62 | nM | 4.70 |