Assay Detail
Binding
CHEMBL4887101
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding assay (PTK2B)
2
Total Activities
2
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Data for DCP probe PF-04554878
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.92 | 9.70 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Target protein length | Target protein length | - | — | kinase domain |
| Target protein type | Target protein type | - | — | human recombinant |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3137331 | DEFACTINIB | 3.0 | 1 | 9.70 |
| CHEMBL4518706 | PF-00911705 | — | 1 | 6.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3137331 | DEFACTINIB | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL4518706 | PF-00911705 | IC50 | = | 721.0 | nM | 6.14 |