Assay Detail
Binding
CHEMBL4887761
Review assay metadata, readout intent, target linkage, and publication context from the same page.
CETSA intact cells
1
Total Activities
1
Compounds Tested
1
Activity Types
2
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha (CHEMBL1795194) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe BAY-091
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 1 | 5.96 | 5.96 |
Assay Parameters
| Parameter | Type | Value | Units | Text |
|---|---|---|---|---|
| Additional information | Additional information | - | — | Cellular thermal shift assay at 56 °C to test cellular engagement |
| Target protein type | Target protein type | - | — | intact cells |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4802045 | BAY-091 | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4802045 | BAY-091 | EC50 | = | 1100.0 | nM | 5.96 |