Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha · SINGLE PROTEIN · Homo sapiens
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As of 2026-09-14Protein identity stays anchored to UniProt P48426. Use UniProt P48426 as the stable identity anchor, then attach disease evidence before program review.
Use UniProt P48426 as the stable identity anchor, then attach disease evidence before program review.
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Review this target as Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, mapped to UniProt P48426. Sequence length is 406 aa.
Protein source · UniProt accession via ChEMBL component mappingKeep the review anchor, source IDs, and context contract aligned before reusing this target elsewhere.
This review treats Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha as ChEMBL target CHEMBL1795194, mapped to UniProt P48426. Disease framing currently uses the Open Targets-ready proxy contract.
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| Preferred Name | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
| Target Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
| UniProt | P48426 |
Reviewable protein naming and mapping context for this target snapshot.
| Protein Label | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha |
| UniProt Accession | P48426 |
| Component Type | Protein |
| Sequence Length | 406 aa |
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha
Review this target as Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha, mapped to UniProt P48426. Sequence length is 406 aa.
| ChEMBL ID | pChEMBL | Type | Value (nM) | Phase |
|---|---|---|---|---|
| CHEMBL4802045 | 9.0 | IC50 | 1.0 | Preclinical |
| CHEMBL5280127 | 8.7 | IC50 | 2.0 | Preclinical |
| CHEMBL5276719 | 8.3 | IC50 | 5.0 | Preclinical |
| CHEMBL5270765 | 8.15 | IC50 | 7.0 | Preclinical |
| CHEMBL5288342 | 8.0 | IC50 | 10.0 | Preclinical |
| CHEMBL5290005 | 7.89 | IC50 | 13.0 | Preclinical |
| CHEMBL5271652 | 7.85 | IC50 | 14.0 | Preclinical |
| CHEMBL5277824 | 7.72 | IC50 | 19.0 | Preclinical |
| CHEMBL5277633 | 7.7 | IC50 | 19.95 | Preclinical |
| CHEMBL5288492 | 7.52 | IC50 | 30.0 | Preclinical |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| single protein format | 58 | 52 | 6.0 |
| cell-based format | 42 | 70 | 6.4 |
| subcellular format | 27 | 4 | 5.8 |
| assay format | 5 | 65 | 6.1 |
| BAO Format | Assays | Compounds | Avg pChEMBL |
|---|---|---|---|
| assay format | 2 | 0 | — |