Assay Detail
Binding
CHEMBL4888140
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Homogeneous Time Resolved Fluorescence (HTRF) assay (AKT1)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
RAC-alpha serine/threonine-protein kinase (CHEMBL4282) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Data for DCP probe Borussertib
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.07 | 9.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | — | 1 | 9.10 |
| CHEMBL4802051 | RL2578 | — | 1 | 5.04 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4795065 | Borussertib | IC50 | = | 0.8 | nM | 9.10 |
| CHEMBL4802051 | RL2578 | IC50 | = | 9200.0 | nM | 5.04 |