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Assay Detail

CHEMBL5029262

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Aspergillus niger alpha-glucosidase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Aspergillus niger
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Positional Isomeric Effects on the Optical Properties, Multivalent Glycosidase Inhibition Effect, and Hypoglycemic Effect of Perylene Bisimide-deoxynojirimycin Conjugates.
Li RF, Yang JX, Liu J, Ai GM, Zhang HY, Xu LY, Chen SB, Zhang HX, Li XL, Cao ZR, Wang KR.
J Med Chem (2021) 64 : 5863 -5873
PubMed 33886333 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 4 4.65 4.88

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL5078012 1 4.88
CHEMBL5090920 1 4.83
CHEMBL1561 MIGLITOL 4.0 1 4.68
CHEMBL5077606 1 4.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL5078012 Kd = 13060.0 nM 4.88
CHEMBL5090920 Kd = 14720.0 nM 4.83
CHEMBL1561 MIGLITOL Kd = 20640.0 nM 4.68
CHEMBL5077606 Kd = 61610.0 nM 4.21