Assay Detail
Binding
CHEMBL5029454
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Binding affinity to human BRD4 bromodomain 1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 3 | 5.67 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3752296 | — | — | 1 | 6.00 |
| CHEMBL5076790 | — | — | 1 | 5.50 |
| CHEMBL5076935 | — | — | 1 | 5.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3752296 | — | Kd | = | 1000.0 | nM | 6.00 |
| CHEMBL5076790 | — | Kd | = | 3162.28 | nM | 5.50 |
| CHEMBL5076935 | — | Kd | = | 3162.28 | nM | 5.50 |