Assay Detail
Binding
CHEMBL5031250
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]-PDBu from recombinant human PKCalpha by scintillation counter method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Characterization of Novel <i>sn</i>-1 Heterocyclic DAG-Lactones as PKC Activators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.37 | 7.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL137386 | — | — | 1 | 7.63 |
| CHEMBL5077090 | — | — | 1 | 7.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL137386 | — | Ki | = | 23.6 | nM | 7.63 |
| CHEMBL5077090 | — | Ki | = | 79.3 | nM | 7.10 |