Assay Detail
Functional
CHEMBL5032420
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Antiproliferative activity against human HL-60 cells incubated for 48 hrs by WST-1 assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
First-in-Class Inhibitors of the Ribosomal Oxygenase MINA53.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 4.50 | 4.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5070745 | — | — | 1 | 4.85 |
| CHEMBL5084638 | — | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5070745 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL5084638 | — | IC50 | = | 73000.0 | nM | 4.14 |