Assay Detail
Functional
CHEMBL5039289
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against MERS-COV expressing S protein Q1020R mutation assessed as reduction in viral infection
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Middle East respiratory syndrome-related coronavirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Middle East respiratory syndrome-related coronavirus (CHEMBL4296578) ↗| Type | ORGANISM |
| Organism | Middle East respiratory syndrome-related coronavirus |
Publication
Supercoiling Structure-Based Design of a Trimeric Coiled-Coil Peptide with High Potency against HIV-1 and Human β-Coronavirus Infection.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.26 | 6.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4127413 | — | — | 1 | 6.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4127413 | — | IC50 | = | 550.0 | nM | 6.26 |