Assay Detail
Binding
CHEMBL5039879
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Binding affinity to CM5 sensor chip immobilized recombinant full-length TRBP (unknown origin) assessed as dissociation constant by SPR analysis
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 4.87 | 5.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5077274 | — | — | 1 | 5.17 |
| CHEMBL463499 | — | — | 1 | 5.09 |
| CHEMBL5090710 | — | — | 1 | 4.75 |
| CHEMBL5093445 | — | — | 1 | 4.74 |
| CHEMBL5092403 | — | — | 1 | 4.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5077274 | — | Kd | = | 6790.0 | nM | 5.17 |
| CHEMBL463499 | — | Kd | = | 8060.0 | nM | 5.09 |
| CHEMBL5090710 | — | Kd | = | 17970.0 | nM | 4.75 |
| CHEMBL5093445 | — | Kd | = | 18310.0 | nM | 4.74 |
| CHEMBL5092403 | — | Kd | = | 24080.0 | nM | 4.62 |