Assay Detail
Functional
CHEMBL5041369
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HL-60 cells assessed as growth inhibition
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Dihydrolucilactaene, a Potent Antimalarial Compound from <i>Fusarium</i> sp. RK97-94.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.66 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | 4.0 | 1 | 8.66 |
| CHEMBL5074822 | — | — | 1 | 4.80 |
| CHEMBL5072627 | — | — | 1 | 4.76 |
| CHEMBL5078419 | — | — | 1 | 4.42 |
| CHEMBL5081190 | — | — | 1 | - |
| CHEMBL5092772 | — | — | 1 | - |
| CHEMBL5086557 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL428647 | PACLITAXEL | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL5074822 | — | IC50 | = | 15800.0 | nM | 4.80 |
| CHEMBL5072627 | — | IC50 | = | 17400.0 | nM | 4.76 |
| CHEMBL5078419 | — | IC50 | = | 37700.0 | nM | 4.42 |
| CHEMBL5081190 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL5092772 | — | IC50 | > | 70000.0 | nM | - |
| CHEMBL5086557 | — | IC50 | > | 70000.0 | nM | - |